✅ What is DES(1-3) IGF-1?

DES(1-3) IGF-1 is a modified, more potent version of IGF-1 (Insulin-like Growth Factor-1). It’s a synthetic peptide where the first three amino acids of regular IGF-1 have been removed. This alteration significantly increases its biological activity.

💡 Key Characteristics

• Length: 67 amino acids (like IGF-1, but missing the first 3).
• Enhanced potency: 5 to 10 times more powerful than standard IGF-1.
• Lower affinity to IGF-binding proteins, which allows it to act more freely.
• Very short half-life: Around 20–30 minutes.

💪 Common (Non-medical) Uses in Bodybuilding

• Stimulates muscle hypertrophy (muscle growth).
• Promotes muscle cell repair and regeneration.
• May enhance nutrient uptake at the cellular level.
• Often injected locally into the muscle for targeted growth.

📊 Comparison: IGF-1 vs DES(1-3) IGF-1

⚠️ Risks and Side Effects

Use of DES(1-3) IGF-1, especially outside clinical settings, carries risks:

• Hypoglycemia (low blood sugar).
• Abnormal tissue growth.
• Headaches, dizziness.
• Insulin resistance.
• Potential cancer risks (as it promotes cell proliferation).
• Not FDA-approved for bodybuilding or anti-aging use.

💉 Typical Usage (for informational purposes only)

⚠️ Not medical advice. For educational purposes only.

• Dosage: 10–50 mcg per day.
• Route: Subcutaneous or intramuscular injection.
• Timing: Often post-workout to support muscle recovery and growth.

🧠 Summary

DES(1-3) IGF-1 is a highly active peptide with strong muscle-building effects, especially when used locally. While its effectiveness is well-known in performance circles, it comes with considerable risks and should only be considered with caution—and ideally under medical supervision